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Nasal polyps, nasal polyp) fat in nasal cavity or sinus mucosa is prominent in the nasal mucous membrane hyperplasia tissue on the surface of the ball. Nasal obstruction or increased nasal secretion is a common manifestation, accompanied by facial pain or swelling, hyposmia or loss of sense of smell. It is nose ministry common disease, good hair at adult, children happens rarely. Can be a single or multiple, more commonly seen in the maxillary sinus, ethmoid sinus, middle nasal tract, middle turbinate, etc.
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The middle nasal passage is characterized by narrow and uneven microenvironment space, and the inhaled airflow is easy to form turbulence. Ciliary function is weakened, ciliary movement disorder; The mucosal blood flow of the middle nasal tract was significantly reduced compared with other parts of the nose. The natural defense function of the middle nasal tract is weakened, and local areas are easily damaged by harmful factors, which creates conditions for the formation of nasal polyps. Many mast cells, eosinophils and IgE generating cells could be found in nasal polyp tissues, and the increased IgE level in the liquid suggested a certain role of local allergy.
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Nearly 90% of nasal polyps have more eosinophilic infiltration, suggesting that nasal polyps are closely related to the proliferation of such cells. Staphylococcus aureus is one of the common symbiotic bacteria in nasal cavity. Staphylococcus aureus enterotoxin can directly activate a large number of Th2 cells, B cells, eosinophils and mast cells in the nasal mucosa of the middle nasal tract, so as to release a large number of pro-inflammatory cytokines, aggravate the local inflammatory reaction in the middle nasal tract, and promote the formation of polyps.
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The pathogenesis of nasal polyps is unclear, and some reports suggest that there may be a potential genetic influence. Nasal polyps are usually familial, suggesting that genetic or environmental factors may play a role in the pathogenesis of nasal polyps. Endoscopic examination of the nasal cavity revealed one or more smooth, grayish white, yellowish or reddish translucent masses such as lychee flesh. Soft touch, no pain, not easy bleeding. Polyp small person must use vasoconstrictor to contract turbinate or use nasal endoscope ability to discover.
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Polyp is big and much person, forward development can dash forward to before nostril, its front end because often get outside air and dust stimulation, show reddish, sometimes the surface has ulcer and scab skin. Nasal polyps develop backward to the posterior nostril and even the nasopharynx. Large nasal polyps can cause external nasal deformation and widen the nasal dorsum to form a "frog nose". Nasal cavity can be seen thin serous or viscous, purulent secretions.
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